Tamodex 20 mg Tamoxifen 100 pill

Tamoxifen Information

Pronunciation

ta MOKS i fen

 

What is this drug used for?

• It is used to treat breast cancer.

• It is used to lower the chance of breast cancer in women with a higher chance of getting it. It may lower the chance of getting cancer in the other breast after one has cancer.

• It may be given to you for other reasons. Talk with the doctor.

Frequently reported side effects of this drug

• Hot flashes

• Nausea

• Vomiting

• Weight loss

• Constipation

• Diarrhea

• Trouble sleeping

• Anxiety

• Weight gain

• Back pain

• Bone pain

• Dizziness

• Muscle pain

• Joint pain

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Infection

• High calcium like weakness, confusion, fatigue, headache, nausea and vomiting, constipation, or bone pain.

• Urinary tract infection like blood in the urine, burning or painful urination, passing a lot of urine, fever, lower abdominal pain, or pelvic pain.

• Severe cerebrovascular disease like change in strength on one side is greater than the other, difficulty speaking or thinking, change in balance, or vision changes.

• Bruising

• Bleeding

• Severe loss of strength and energy

• Swelling of arms or legs

• Burning or numbness feeling

• Pelvic pain or pressure

• Menstrual changes

• No menstrual periods

• Abnormal vaginal bleeding

• Vaginal discharge

• Vision changes

• Lump in breast

• Breast soreness or pain

• Decreased sex drive

• Sexual dysfunction

• Depression

• Skin changes

• Severe headache

• Painful urination

• Blood clots like numbness or weakness on one side of the body; pain, redness, tenderness, warmth, or swelling in the arms or legs; change in color of an arm or leg; chest pain; shortness of breath; fast heartbeat; or coughing up blood.

• Liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin.

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

 

Medication Safety Issues

Sound-alike/look-alike issues:

 

Storage and Stability

Oral solution: Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F). Do not freeze or refrigerate. Protect from light. Discard opened bottle after 3 months.

Tablets: Store at 20°C to 25°C (68°F to 77°F). Protect from light. Avoid excessive heat.

 

Adverse Reactions

Cardiovascular: Cerebrovascular accident, chest pain, deep vein thrombosis, edema, flushing, hypertension, ischemic heart disease, peripheral edema, vasodilation, venous thrombosis

Dermatologic: Alopecia, diaphoresis, pruritus vulvae, skin changes, skin rash

Endocrine & metabolic: Amenorrhea, fluid retention, hot flash, hypercalcemia, hypercholesterolemia, infrequent uterine bleeding, menstrual disease, ovarian cyst, weight gain, weight loss

Gastrointestinal: Abdominal cramps, abdominal pain, anorexia, cholestasis, constipation, diarrhea, dysgeusia, dyspepsia, nausea, nausea and vomiting

Genitourinary: Irregular menses, leukorrhea, mastalgia, urinary tract infection, vaginal discharge, vaginal dryness, vaginal hemorrhage, vaginitis, vulvovaginitis

Hematologic & oncologic: Anemia, breast neoplasm, lymphedema, neoplasm (second primary), thrombocytopenia, tumor flare (during treatment of metastatic breast cancer; generally resolves with continuation; includes increased lesion size and erythema)

Hepatic: Hepatic necrosis, hepatitis, increased serum aspartate aminotransferase, increased serum bilirubin, liver steatosis

Hypersensitivity: Hypersensitivity reaction

Infection: Infection, sepsis

Nervous system: Anxiety, depression, dizziness, fatigue, headache, insomnia, mood changes, pain, paresthesia, tumor pain (during treatment of metastatic breast cancer; generally resolves with continuation)

Neuromuscular & skeletal: Arthralgia, arthritis, arthropathy, asthenia, back pain, bone fracture, musculoskeletal pain, myalgia, ostealgia, osteoporosis

Ophthalmic: Cataract

Renal: Increased serum creatinine

Respiratory: Bronchitis, cough, dyspnea, flu-like symptoms, pharyngitis, sinusitis, throat irritation (oral solution)

Miscellaneous: Cyst

Rare: Hepatic neoplasm, superficial thrombophlebitis