Levofloxacin Information
Pronunciation
lee voe FLOKS a sin
What is this drug used for?
– It is used to treat bacterial infections.
Frequently reported side effects of this drug
– Constipation
– Nausea
– Diarrhea
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
– Kidney problems like unable to pass urine, blood in the urine, change in amount of urine passed, or weight gain.
– Stevens-Johnson syndrome/toxic epidermal necrolysis like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in mouth, throat, nose, or eyes.
– Tendon inflammation or rupture like pain, bruising, or swelling in the back of the ankle, shoulder, hand, or other joints.
– Depression like thoughts of suicide, anxiety, emotional instability, or confusion.
– Liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin.
– High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit.
– Low blood sugar like dizziness, headache, fatigue, feeling weak, shaking, fast heartbeat, confusion, increased hunger, or sweating.
– Noise or ringing in the ears
– Chest pain
– Fast heartbeat
– Abnormal heartbeat
– Passing out
– Dizziness
– Severe loss of strength and energy
– Muscle pain
– Muscle weakness
– Difficulty focusing
– Trouble with memory
– Trouble sleeping
– Agitation
– Restlessness
– Vision changes
– Sensing things that seem real but are not
– Anxiety
– Nightmares
– Confusion
– Behavioral changes
– Mood changes
– Seizures
– Severe headache
– Shortness of breath
– Bruising
– Bleeding
– Tremors
– Abnormal gait
– Vaginal pain, itching, and discharge
– Thrush
– Chills
– Severe or persistent abdominal pain
– Severe or persistent chest pain
– Severe or persistent back pain
– Nerve problems like sensitivity to heat or cold; decreased sense of touch; burning, numbness, or tingling; pain, or weakness in the arms, hands, legs, or feet.
-?Clostridioides?(formerly?Clostridium)?difficile-associated diarrhea like abdominal pain or cramps, severe diarrhea or watery stools, or bloody stools.
– Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Medication Safety Issues
Sound-alike/look-alike issues:
Levaquin may be confused with Levoxyl, Levsin/SL, Lovenox
LevoFLOXacin may be confused with levETIRAcetam, levodopa, Levophed, levothyroxine
International issues:
Levaquin [Argentina, Brazil, US, Venezuela] may be confused with Lariam brand name for mefloquine [multiple international markets]
Storage and Stability
Solution for injection:
Vial: Store at room temperature. Protect from light. Diluted solution (5 mg/mL) is stable in NS, D5W, D5NS, D5LR, D51/2NS with 20 mEq/L KCl, Plasma-Lyte 56 in D5, or sodium lactate for 72 hours when stored at room temperature; stable for 14 days when stored under refrigeration. When frozen, stable for 6 months; do not refreeze. Do not thaw in microwave or by bath immersion.
Premixed: Store at ?25?C (77?F); do not freeze. Brief exposure to 40?C (104?F) does not adversely affect the product. Protect from light.
Tablet, oral solution: Store at 25?C (77?F); excursions permitted to 15?C to 30?C (59?F to 86?F).
Adverse Reactions
Cardiovascular: Chest pain, edema
Central nervous system: Dizziness, headache, insomnia
Dermatologic: Pruritus, skin rash
Gastrointestinal: Abdominal pain, constipation, diarrhea, dyspepsia, nausea, vomiting
Genitourinary: Vaginitis
Infection: Candidiasis
Local: Injection site reaction
Respiratory: Dyspnea
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