Frusenex 100 mg Frusemide 100 tablets

Furosemide Information

Pronunciation

fyoor OH se mide

 

What is this drug used for?

• It is used to get rid of extra fluid.

• It is used to treat high blood pressure.

Frequently reported side effects of this drug

• Constipation

• Lack of appetite

• Abdominal cramps

• Diarrhea

• Nausea

• Vomiting

• Headache

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, abnormal heartbeat, severe dizziness, passing out, fast heartbeat, increased thirst, seizures, loss of strength and energy, lack of appetite, unable to pass urine or change in amount of urine passed, dry mouth, dry eyes, nausea, or vomiting.

• High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit.

• Liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin.

• Kidney problems like unable to pass urine, blood in the urine, change in amount of urine passed, or weight gain.

• Pancreatitis like severe abdominal pain, severe back pain, severe nausea, or vomiting.

• Infection

• Severe dizziness

• Passing out

• Burning or numbness feeling

• Blurred vision

• Agitation

• Severe loss of strength and energy

• Bruising

• Bleeding

• Noise or ringing in the ears

• Trouble hearing

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

 

Medication Safety Issues

Sound-alike/look-alike issues:

 

Storage and Stability

Injection: Store at room temperature. Protect from light. Exposure to light may cause discoloration; do not use furosemide solutions if they have a yellow color. Furosemide solutions are unstable in acidic media, but very stable in basic media. Refrigeration may result in precipitation or crystallization; however, resolubilization at room temperature or warming may be performed without affecting the drug’s stability. Infusion solution in D5W, NS, or LR is stable for 24 hours at room temperature.

Tablet, solution: Store at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 89°F). Protect from light. Discard opened bottle of solution after 90 days (10 mg/mL concentration only).

 

Adverse Reactions

Cardiovascular: Necrotizing angiitis, orthostatic hypotension, thrombophlebitis, vasculitis

Central nervous system: Dizziness, headache, paresthesia, restlessness, vertigo

Dermatologic: Acute generalized exanthematous pustulosis, bullous pemphigoid, erythema multiforme, exfoliative dermatitis, pruritus, skin photosensitivity, skin rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria

Endocrine & metabolic: Glycosuria, hyperglycemia, hyperuricemia, increased serum cholesterol, increased serum triglycerides

Gastrointestinal: Abdominal cramps, anorexia, constipation, diarrhea, gastric irritation, mouth irritation, nausea, pancreatitis, vomiting

Genitourinary: Bladder spasm

Hematologic & oncologic: Agranulocytosis, anemia, aplastic anemia, eosinophilia, hemolytic anemia, leukopenia, purpura, thrombocytopenia

Hepatic: Hepatic encephalopathy, intrahepatic cholestatic jaundice, liver enzymes increased

Hypersensitivity: Anaphylaxis, anaphylactoid reaction, anaphylactic shock

Immunologic: DRESS syndrome

Neuromuscular & skeletal: Muscle spasm, weakness

Ophthalmic: Blurred vision, xanthopsia

Otic: Deafness, tinnitus

Renal: Interstitial nephritis (allergic), renal disease

Miscellaneous: Fever