Tinidazole Information
What is this drug used for?
– It is used to treat infections.
Possible side effects
Tinidazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
– Bad taste in your mouth.
– Upset stomach.
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
– Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
– A burning, numbness, or tingling feeling that is not normal.
– Seizures.
– Vaginal itching or discharge.
Storage and Stability
Store at 20?C to 25?C (68?F to 77?F); excursions permitted to 15?C to 30?C (59?F to 86?F). Protect from light.
Adverse Reactions
1% to 10%:
Central nervous system: Fatigue (?2%), malaise (?2%), dizziness (?1%), headache (?1%)
Dermatologic: Body odor (vaginal: >2%)
Endocrine & metabolic: Hypermenorrhea (>2%)
Gastrointestinal: Dysgeusia (bitter taste, metallic taste: 4% to 6%), nausea (3% to 5%), anorexia (2% to 3%), decreased appetite (>2%), flatulence (>2%), dyspepsia (?2%), abdominal cramps (?2%), epigastric distress (?2%), vomiting (1% to 2%), constipation (?1%)
Genitourinary: Vulvovaginal candidiasis (5%), dysuria (>2%), pelvic pain (>2%), urine abnormality (>2%), vulvovaginal disease (discomfort) (>2%)
Neuromuscular & skeletal: Weakness (1% to 2%)
Renal: Urinary tract infection (>2%)
Respiratory: Upper respiratory tract infection (>2%)
Frequency not defined:
Cardiovascular: Flushing, palpitations
Central nervous system: Ataxia, burning sensation, drowsiness, insomnia, peripheral neuropathy (transient; includes numbness and paresthesia), seizure, vertigo
Dermatologic: Diaphoresis, pruritus, skin rash, urticaria
Endocrine & metabolic: Increased thirst
Gastrointestinal: Abdominal pain, diarrhea, oral candidiasis, salivation, stomatitis, tongue discoloration, xerostomia
Genitourinary: Dark urine, vaginal discharge
Hematologic & oncologic: Leukopenia (transient), neutropenia (transient)
Hepatic: Increased serum transaminases
Hypersensitivity: Angioedema
Infection: Candidiasis (overgrowth)
Neuromuscular & skeletal: Arthralgia, arthritis, myalgia
Miscellaneous: Fever
<1%, postmarketing, and/or case reports: Bronchospasm, coma, confusion, depression, dyspnea, erythema multiforme, hairy tongue, hypersensitivity reaction (acute, severe), pharyngitis, Stevens-Johnson syndrome, thrombocytopenia (reversible)
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