What is this drug used for?
– It is used to treat hiccups.
– It is used to treat tetanus.
– It is used to treat problems with how one acts.
– It is used to treat acute intermittent porphyria.
– It is used to treat mania.
– It is used to treat upset stomach and throwing up.
– It is used to treat schizophrenia.
– It is used to ease anxiety before surgery.
– It may be given to you for other reasons. Talk with the doctor.
Frequently reported side effects of this drug
– Constipation
– Dry mouth
– Fatigue
– Stuffy nose
– Nausea
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
– Infection
– Neuroleptic malignant syndrome like fever, muscle cramps or stiffness, dizziness, severe headache, confusion, change in thinking, fast heartbeat, abnormal heartbeat, or sweating a lot.
– High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit.
– Low blood sugar like dizziness, headache, fatigue, feeling weak, shaking, fast heartbeat, confusion, increased hunger, or sweating.
– Tardive dyskinesia like unable to control body movements; tongue, face, mouth, or jaw sticking out; mouth puckering; or puffing cheeks.
– Fast heartbeat
– Yellow skin
– Abnormal heartbeat
– Erection that lasts more than 4 hours
– Abnormal movements
– Twitching
– Change in balance
– Agitation
– Muscle weakness
– Difficulty swallowing
– Difficulty speaking
– Dizziness
– Passing out
– Tremors
– Difficulty moving
– Rigidity
– Drooling
– Behavioral changes
– Seizures
– Swelling of arms or legs
– Vision changes
– Bruising
– Bleeding
– Enlarged breasts
– Nipple discharge
– Sexual dysfunction
– No menstrual periods
– Difficult urination
– Unable to pass urine
– Severe loss of strength and energy
– Trouble sleeping
– Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Note:?This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.
Pronunciation
(klor PROE ma zeen)
Medication Safety Issues
Sound-alike/look-alike issues:
ChlorproMAZINE may be confused with chlordiazePOXIDE, chlorproPAMIDE, clomiPRAMINE, prochlorperazine, promethazine
Thorazine may be confused with thiamine, thioridazine
Storage and Stability
Oral: Store at 20?C to 25?C (68?F to 77?F); protect from light and moisture.
Injection solution: Store at 20?C to 25?C (68?F to 77?F); excursions permitted to 15?C to 30?C (59?F to 86?F). Protect from light and freezing. A slightly yellowed solution does not indicate potency loss, but a markedly discolored solution should be discarded.
Adverse Reactions
Cardiovascular: ECG abnormality (nonspecific QT changes), orthostatic hypotension, syncope, tachycardia
Central nervous system: Brain edema, catatonic-like state, dizziness, drowsiness, dystonia, extrapyramidal reaction, hyperpyrexia, neuroleptic malignant syndrome, parkinsonism, psychotic symptoms, restlessness, tardive dyskinesia, tardive dystonia
Dermatologic: Contact dermatitis, cutaneous lupus erythematosus (Pavlidakey 1985), skin photosensitivity, skin pigmentation (slate gray)
Endocrine & metabolic: Weight gain
Gastrointestinal: Atony of colon, constipation, increased appetite, nausea, obstipation, paralytic ileus, xerostomia
Genitourinary: Breast engorgement, ejaculatory disorder, false positive pregnancy test, impotence, lactation, priapism, urinary retention
Hematologic & oncologic: Agranulocytosis, aplastic anemia, eosinophilia, hemolytic anemia, immune thrombocytopenia, leukopenia
Hepatic: Jaundice
Hypersensitivity: Nonimmune anaphylaxis
Neuromuscular & skeletal: Lupus-like syndrome (Pavlidakey 1985)
Ophthalmic: Corneal deposits, lens disease (deposits), miosis, mydriasis, star-shaped cataract, visual impairment
Respiratory: Nasal congestion
Miscellaneous: Low fever
Postmarketing: Abnormal proteins in cerebrospinal fluid, amenorrhea, angioedema, asthma, epithelial keratopathy, exfoliative dermatitis, glycosuria, gynecomastia, hyperglycemia, hypoglycemia, laryngeal edema, pancytopenia, peripheral edema, retinitis pigmentosa, seizure
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