Amantadine Information
Pronunciation
(a MAN ta deen)
What is this drug used for?
– It is used to treat or prevent the flu.
– It is used to treat Parkinson’s disease and side effects caused by some other drugs.
– It may be given for other reasons. Talk with the doctor.
Frequently reported side effects of this drug
– Dry mouth
– Constipation
– Lack of appetite
– Abnormal dreams
– Dry nose
– Diarrhea
– Loss of strength and energy
– Tablet shell in stool
– Nausea
– Headache
– Anxiety
– Trouble sleeping
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
– Confusion
– Severe dizziness
– Passing out
– Sensing things that seem real but are not
– Seizures
– Shortness of breath
– Excessive weight gain
– Swelling of arms or legs
– Difficult urination
– Blurred vision
– Uncontrollable urges
– Change in balance
– Falls
– Depression like thoughts of suicide, anxiety, emotional instability, agitation, irritability, panic attacks, mood changes, behavioral changes, or confusion
– Skin growths
– Mole changes
– Urinary tract infection like blood in the urine, burning or painful urination, passing a lot of urine, fever, lower abdominal pain, or pelvic pain.
– Narcolepsy
– Severe fatigue
– Neuroleptic malignant syndrome like fever, muscle cramps or stiffness, dizziness, severe headache, confusion, change in thinking, fast heartbeat, abnormal heartbeat, or sweating a lot.
– Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Medication Safety Issues
Sound-alike/look-alike issues:
Amantadine may be confused with amiodarone, raNITIdine, riMANTAdine
Symmetrel may be confused with Synthroid
Storage and Stability
Store at 20?C to 25?C (68?F to 77?F); excursions permitted to 15?C to 30?C (59?F to 86?F). Protect immediate-release capsules from moisture and exposure to light.
Adverse Reactions
Cardiovascular: Livedo reticularis (may be more common in women), orthostatic hypotension (may be more common in men), peripheral edema, presyncope, syncope
Central nervous system: Abnormal dreams (may be more common in women), agitation, anxiety, apathy, ataxia (may be more common in men and adults ?65 years old), confusion, delusions, depression, dizziness, drowsiness, dyschromia, dystonia, falling, fatigue, hallucination, headache, illusion, insomnia, irritability, nervousness, paranoia, suicidal ideation
Gastrointestinal: Anorexia, constipation, decreased appetite, diarrhea, nausea (may be more common in women), vomiting, xerostomia (may be more common in women)
Genitourinary: Benign prostatic hypertrophy, urinary tract infection
Hematologic & oncologic: Bruise
Neuromuscular & skeletal: Joint swelling, muscle spasm
Ophthalmic: Blurred vision, cataract (may be more common in women), xerophthalmia
Respiratory: Cough, dry nose
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