OMNACORTIL (Prednisone)20mg – 300 tablet


Each Omnacortil contains 2.5 mg Prednisolone 100 tablets. It is used for allergy, asthma, adrenal gland, blood problems, skin rashes, or swelling problems.

ATC Classification: A07EA03, H02AB07
Active Ingrediant: Prednisolone
Generic Name: OMNACORTIL
Manufacturer: Macleods Pharma
Strength: 20mg
Dosage Type: Tablet
Packaging Type: Foil in Box
Contains: 300 Tab


What is this drug used for?

• It is used for many health problems like allergy signs, asthma, adrenal gland problems, blood problems, skin rashes, or swelling problems. This is not a list of all health problems that this drug may be used for. Talk with the doctor.

Frequently reported side effects of this drug

• Nausea

• Vomiting

• Trouble sleeping

• Restlessness

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Infection

• High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit

• Adrenal gland problems like severe nausea, vomiting, severe dizziness, passing out, muscle weakness, severe fatigue, mood changes, lack of appetite, or weight loss

• Low potassium like muscle pain or weakness, muscle cramps, or an abnormal heartbeat

• Pancreatitis like severe abdominal pain, severe back pain, severe nausea, or vomiting

• Cushing syndrome like weight gain in upper back or abdomen; moon face; severe headache; or slow healing

• Skin changes like acne, stretch marks, slow healing, or hair growth

• DVT like swelling, warmth, numbness, change in color, or pain in the extremities

• Severe loss of strength and energy

• Fast heartbeat

• Confusion

• Sweating a lot

• Dizziness

• Passing out

• Shortness of breath

• Excessive weight gain

• Swelling of arms or legs

• Severe headache

• Fast heartbeat

• Slow heartbeat

• Abnormal heartbeat

• Chest pain

• Menstrual changes

• Joint pain

• Bone pain

• Vision changes

• Mood changes

• Behavioral changes

• Trouble with memory

• Trouble focusing

• Sensing things that seem real but are not

• Seizures

• Burning or numbness feeling

• Bruising

• Bleeding

• Severe abdominal pain

• Black, tarry, or bloody stools

• Vomiting blood

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

Note: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.



(PRED ni sone)


Medication Safety Issues

Sound-alike/look-alike issues:

PredniSONE may be confused with methylPREDNISolone, Pramosone, prazosin, prednisoLONE, PriLOSEC, primidone, promethazine


Generic Availability: US

May be product dependent


Storage and Stability

Store at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light and moisture.

Oral solution, concentrate: Discard opened bottle after 90 days.


Adverse Reactions

Cardiovascular: Cardiac failure (in susceptible patients), hypertension

Central nervous system: Emotional lability, headache, increased intracranial pressure (with papilledema), myasthenia, psychiatric disturbance (including euphoria, insomnia, mood swings, personality changes, severe depression), seizure, vertigo

Dermatologic: Diaphoresis, facial erythema, skin atrophy, urticaria

Endocrine & metabolic: Cushing’s syndrome, decreased serum potassium, diabetes mellitus, fluid retention, growth suppression (children), hypokalemic alkalosis, hypothyroidism (enhanced), menstrual disease, negative nitrogen balance (due to protein catabolism), sodium retention

Gastrointestinal: Abdominal distention, carbohydrate intolerance, pancreatitis, peptic ulcer (with possible perforation and hemorrhage), ulcerative esophagitis

Hematologic & oncologic: Bruise, Kaposi’s sarcoma, petechia

Hepatic: Increased serum alkaline phosphatase, increased serum ALT, increased serum AST

Hypersensitivity: Anaphylaxis, hypersensitivity reaction

Infection: Infection

Neuromuscular & skeletal: Amyotrophy, aseptic necrosis of bones (femoral and humeral heads), osteoporosis, pathological fracture (long bones), rupture of tendon (particularly Achilles tendon), steroid myopathy, vertebral compression fracture

Ophthalmic: Exophthalmos, glaucoma, increased intraocular pressure, subcapsular posterior cataract

Miscellaneous: Wound healing impairment

Rare but important or life-threatening: Venous thrombosis (Johannesdottir 2013)


Macleods Pharma

Additional information

Active Ingrediant

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Alternate Names

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Dosage Type

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